{"id":17069,"date":"2020-11-04T16:40:06","date_gmt":"2020-11-04T13:40:06","guid":{"rendered":"https:\/\/medimall.gr\/thromvofilia-pos-epireazei-ti-gynaikeia-ygeia-kai-gonimotita\/"},"modified":"2022-06-14T18:07:18","modified_gmt":"2022-06-14T15:07:18","slug":"thrombophilie-comment-affecte-t-elle-la-sante-et-la-fertilite-femmes","status":"publish","type":"post","link":"https:\/\/medimall.gr\/fr\/thrombophilie-comment-affecte-t-elle-la-sante-et-la-fertilite-femmes\/","title":{"rendered":"\u03a4hrombophilie: comment affecte-t-elle la sant\u00e9 et la fertilit\u00e9 des femmes?"},"content":{"rendered":"

Qu’est-ce que la thrombophilie, comment est-elle li\u00e9e \u00e0 la fertilit\u00e9 f\u00e9minine et comment est-elle trait\u00e9e?<\/span><\/h3>\n

La thrombophilie peut \u00eatre d\u00e9finie comme une anomalie h\u00e9r\u00e9ditaire ou acquise qui pr\u00e9dispose \u00e0 la survenue de thromboses (caillots sanguins). Elle constitue un facteur de risque d\u2019obstruction partielle ou totale de certains vaisseaux sanguins.<\/p>\n

La thrombophilie, qu’est-ce que c’est ?<\/strong><\/p>\n

D\u00e9finition de la thrombophilie<\/strong><\/p>\n

La thrombophilie est un terme m\u00e9dical qui regroupe plusieurs anomalies pr\u00e9disposant \u00e0 la formation de caillots sanguins. Ce sont des anomalies de l\u2019h\u00e9mostase, c\u2019est-\u00e0-dire des anomalies affectant les m\u00e9canismes contribuant \u00e0 l\u2019arr\u00eat des saignements en cas de br\u00e8che dans un vaisseau sanguin.<\/p>\n

En d\u2019autres termes, une personne thrombophile pr\u00e9sente des troubles de la coagulation qui favorisent la formation de caillots sanguins. Un caillot, caillot sanguin ou thrombus est un petit agglom\u00e9rat visqueux constitu\u00e9 de cellules sanguines. Le d\u00e9veloppement de caillots sanguins peut \u00eatre \u00e0 l\u2019origine de complications graves car ils peuvent provoquer une obstruction de certains vaisseaux sanguins. Les organes ne sont plus correctement aliment\u00e9s et ne peuvent plus assurer leurs r\u00f4les.<\/p>\n

Causes des thrombophilie<\/strong><\/p>\n

Les thrombophilies peuvent \u00eatre cong\u00e9nitales ou acquises, c\u2019est-\u00e0-dire pr\u00e9sentes d\u00e8s la naissance ou survenues au cours de la vie.<\/p>\n

Les thrombophilies cong\u00e9nitales sont le plus souvent h\u00e9r\u00e9ditaires (transmises par les parents). Les principales causes de trombrophilies cong\u00e9nitales sont :<\/strong><\/p>\n

les d\u00e9ficits en antithrombine, en prot\u00e9ine C ou en prot\u00e9ine S, qui sont des facteurs inhibiteurs de la coagulation ;<\/p>\n

la mutation du facteur V Leiden entra\u00eenant une r\u00e9sistance \u00e0 la prot\u00e9ine C ;<\/p>\n

la mutation G 20210 A sur le g\u00e8ne de la prothrombine qui est une prot\u00e9ine de la coagulation ;<\/p>\n

les exc\u00e8s de facteur VIII intervenant dans la coagulation sanguine ;<\/p>\n

l’ hyperhomocyst\u00e9in\u00e9mie qui correspond \u00e0 des taux \u00e9lev\u00e9s d\u2019homocyst\u00e9ine (acide amin\u00e9 sp\u00e9cifique) dans le sang.<\/p>\n

Les thrombophilies acquises sont quant \u00e0 elles g\u00e9n\u00e9ralement dues \u00e0 un syndrome des anti-phospholipides. Il s\u2019agit d\u2019une maladie auto-immune, c\u2019est-\u00e0-dire une maladie provoqu\u00e9e par un dysfonctionnement du syst\u00e8me immunitaire. Celui-ci produit des anticorps (mol\u00e9cules de d\u00e9fense de l\u2019organisme) anormaux qui vont attaquer des constituants essentiels du corps. Dans le cas du syndrome des anti-phospholipides, ces anticorps sont dirig\u00e9s contre les phospholipides (principaux constituants des membranes des cellules de l\u2019organisme) ou \u00e0 des \u00e9l\u00e9ments li\u00e9s aux phospholipides.<\/p>\n

Diagnostic de la thrombophilie<\/strong><\/p>\n

La thrombophilie est diagnostiqu\u00e9e gr\u00e2ce \u00e0 un bilan de thrombophilie. Celui-ci vise \u00e0 rechercher des facteurs cong\u00e9nitaux ou acquis de thrombophilie. Il consiste notamment \u00e0 :<\/p>\n

\u00e9valuer l\u2019activit\u00e9 des prot\u00e9ines inhibitrices de la coagulation ;<\/p>\n

rechercher des mutations g\u00e9n\u00e9tiques ;<\/p>\n

rechercher les anticorps du syndrome des anti-phospholipides.<\/p>\n

Les sympt\u00f4mes des thrombophillies<\/p>\n

Formation de caillots sanguins<\/p>\n

La thrombophilie d\u00e9signe en quelque sorte un \u00e9tat de pr\u00e9disposition \u00e0 la survenue de thrombose (caillots sanguins).<\/p>\n

Risques de complications<\/strong><\/p>\n

Un risque majeur de thrombophilie est la survenue d\u2019une maladie thromboembolique veineuse. Celle-ci rassemble la thrombose veineuse profonde (ou\u00a0phl\u00e9bite\u00a0profonde) et sa complication imm\u00e9diate : l\u2019embolie pulmonaire. Celle-ci correspond \u00e0 l\u2019obstruction d’une ou plusieurs art\u00e8res irriguant le poumon. Elle provoque des dommages au niveau du poumon atteint et celui-ci ne peut plus fournir d\u2019oxyg\u00e8ne \u00e0 l\u2019organisme. Une prise en charge en urgence est indispensable car elle met en jeu le pronostic vital.<\/p>\n

Les traitements des thrombophilies<\/strong><\/p>\n

La prise \u00e0 charge de la thrombophilie consiste \u00e0 pr\u00e9venir le risque de complications. Elle peut notamment reposer sur :<\/p>\n

la prescription d\u2019anticoagulants tels que les h\u00e9parines non fractionn\u00e9es et les h\u00e9parines de bas poids mol\u00e9culaire ;<\/p>\n

la compression veineuse \u00e9lastique, notamment par le port de bas ou chaussettes de contention;<\/p>\n

l\u2019usage de thrombolytiques, des m\u00e9dicaments visant \u00e0 dissoudre les caillots sanguins.<\/p>\n

Pr\u00e9venir la thrombophilie<\/strong><\/p>\n

Il n\u2019existe pas de mesures pr\u00e9ventives \u00e0 la thrombophilie. En revanche, il est possible de pr\u00e9venir les risques de complications gr\u00e2ce aux traitements pr\u00e9ventifs \u00e9voqu\u00e9s pr\u00e9c\u00e9demment (anticoagulants, compression veineuse \u00e9lastique, thrombolytiques).<\/p>\n

 <\/p>\n

 <\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Qu’est-ce que la thrombophilie, comment est-elle li\u00e9e \u00e0 la fertilit\u00e9 f\u00e9minine et comment est-elle trait\u00e9e? La thrombophilie peut \u00eatre d\u00e9finie comme une anomalie h\u00e9r\u00e9ditaire ou acquise qui pr\u00e9dispose \u00e0 la survenue de thromboses (caillots sanguins). Elle constitue un facteur de risque d\u2019obstruction partielle ou totale de certains vaisseaux sanguins. La thrombophilie, qu’est-ce que c’est ? […]<\/p>\n","protected":false},"author":2,"featured_media":9893,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[22],"tags":[645,2162,2163,2164,2165,407],"featured_image_src":{"landsacpe":["https:\/\/medimall.gr\/wp-content\/uploads\/2020\/11\/thumbnail_onderzoek-bewijst-natuurlijke-bevalling-na-keizersnede-niet-zonder-gevaar-1-1140x445.jpg",1140,445,true],"list":["https:\/\/medimall.gr\/wp-content\/uploads\/2020\/11\/thumbnail_onderzoek-bewijst-natuurlijke-bevalling-na-keizersnede-niet-zonder-gevaar-1-463x348.jpg",463,348,true],"medium":["https:\/\/medimall.gr\/wp-content\/uploads\/2020\/11\/thumbnail_onderzoek-bewijst-natuurlijke-bevalling-na-keizersnede-niet-zonder-gevaar-1-300x150.jpg",300,150,true],"full":["https:\/\/medimall.gr\/wp-content\/uploads\/2020\/11\/thumbnail_onderzoek-bewijst-natuurlijke-bevalling-na-keizersnede-niet-zonder-gevaar-1.jpg",1280,640,false]},"yoast_head":"\n\u03a4hrombophilie: comment affecte-t-elle la sant\u00e9 et la fertilit\u00e9 des femmes? 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